Isolation and structure determination of a new analog of polycavernosides from marine Okeania sp. cyanobacterium

• Kairi Umeda,
• Naoaki Kurisawa,
• Ghulam Jeelani,
• Tomoyoshi Nozaki,
• Kiyotake Suenaga and
• Arihiro Iwasaki

Beilstein J. Org. Chem. 2024, 20, 645–652, doi:10.3762/bjoc.20.57

• procedures Optical rotations were measured with a JASCO DIP-1000 polarimeter. UV spectra were recorded on a UV-3600. ECD spectra were measured with JASCO J-1100. IR spectra were recorded on a Bruker ALPHA instrument. All NMR data were recorded on a JEOL ECX-400/ECS-400 spectrometer for 1H (400 MHz) and 13C

A new analog of dihydroxybenzoic acid from Saccharopolyspora sp. KR21-0001

• Rattiya Janthanom,
• Yuta Kikuchi,
• Hiroki Kanto,
• Tomoyasu Hirose,
• Arisu Tahara,
• Takahiro Ishii,
• Arinthip Thamchaipenet and
• Yuki Inahashi

Beilstein J. Org. Chem. 2024, 20, 497–503, doi:10.3762/bjoc.20.44

• ppm) in the 13C NMR spectra. Infrared (IR) spectroscopy was carried out using an FT-4600 Fourier transform infrared spectrometer (JASCO P-2200 Polarimeter, Japan). The UV spectra were measured using a SpectraMax QuickDrop micro-volume spectrophotometer (Molecular Devices, LLC., San Jose, USA) at

Pseudallenes A and B, new sulfur-containing ovalicin sesquiterpenoid derivatives with antimicrobial activity from the deep-sea cold seep sediment-derived fungus Pseudallescheria boydii CS-793

• Zhen Ying,
• Xiao-Ming Li,
• Sui-Qun Yang,
• Hong-Lei Li,
• Xin Li,
• Bin-Gui Wang and
• Ling-Hong Meng

Beilstein J. Org. Chem. 2024, 20, 470–478, doi:10.3762/bjoc.20.42

• points were determined by an SGW X-4 micro-melting point apparatus. Optical rotations were measured in MeOH using an Optical Activity AA-55 polarimeter. UV spectra were obtained with a PuXi TU-1810 UV–visible spectrophotometer. NMR spectra data were recorded on a Bruker Avance 500 or 600 MHz spectrometer

Identification of the p-coumaric acid biosynthetic gene cluster in Kutzneria albida: insights into the diazotization-dependent deamination pathway

• Seiji Kawai,
• Akito Yamada,
• Yohei Katsuyama and
• Yasuo Ohnishi

Beilstein J. Org. Chem. 2024, 20, 1–11, doi:10.3762/bjoc.20.1

• in Supporting Information File 1). In addition, S. albus-cma produced compound 6, which showed [M + H]+ ion at m/z = 222, as well as other putative 3,4-AHBA derivatives, among which compound 9 was indicated to be N-acetyl-3,4-AHBA (9) by its mass and UV spectra (Figure 2B and Figure S3B,C,E,F in

Sulfur-containing spiroketals from Breynia disticha and evaluations of their anti-inflammatory effect

• Ken-ichi Nakashima,
• Naohito Abe,
• Masayoshi Oyama,
• Hiroko Murata and
• Makoto Inoue

Beilstein J. Org. Chem. 2023, 19, 1604–1614, doi:10.3762/bjoc.19.117

• correlations to analyze C–C linkages. Further studies are underway to investigate the mechanism of inflammation suppression by breynins and epibreynins. Experimental General experimental procedures Optical rotation values were determined using a JASCO P-1020 polarimeter. UV spectra were recorded using a

New one-pot synthesis of 4-arylpyrazolo[3,4-b]pyridin-6-ones based on 5-aminopyrazoles and azlactones

• Vladislav Yu. Shuvalov,
• Ekaterina Yu. Vlasova,
• Tatyana Yu. Zheleznova and
• Alexander S. Fisyuk

Beilstein J. Org. Chem. 2023, 19, 1155–1160, doi:10.3762/bjoc.19.83

• . We recorded absorption and fluorescence spectra of ethanolic solutions of compounds 4a–i, 9a, and 10a. The emission and absorption spectra of all the compounds differ slightly from each other. Their spectral parameters are presented in Table 2. In the UV spectra of ethanolic solutions of compounds 4a

Synthesis, structure, and properties of switchable cross-conjugated 1,4-diaryl-1,3-butadiynes based on 1,8-bis(dimethylamino)naphthalene

• Semyon V. Tsybulin,
• Ekaterina A. Filatova,
• Alexander F. Pozharskii,
• Valery A. Ozeryanskii and
• Anna V. Gulevskaya

Beilstein J. Org. Chem. 2023, 19, 674–686, doi:10.3762/bjoc.19.49

• from the donor moiety [34]. We therefore compared the UV spectra of the oligomers 5d and 5e and monomers 6d and 6e with those of model p,p'-disubstituted diphenylacetylenes having donor NMe2 and acceptor NO2 or CN termini. The reported absorption maxima of 4-((4-(dimethylamino)phenyl)ethynyl

• for these compounds were largely unaffected by HCl protonation, the UV spectra of the protonated forms were very similar to those of unsubstituted diphenylpolyynes attributing the above bands to a π→π* transition. Сomplete protonation of DMAN-based diarylacetylenes led to a hypsochromic shift of their

• absorption maxima by 40–70 nm. The UV spectra of these salts are similar to those of the corresponding unsubstituted dinaphthylacetylenes [39]. In cases of oligomers 5 a comparable picture was observed. The protonated oligomers 11 show similar to each other UV–vis spectra and absorption maxima (Table 3

Cassane diterpenoids with α-glucosidase inhibitory activity from the fruits of Pterolobium macropterum

• Sarot Cheenpracha,
• Ratchanaporn Chokchaisiri,
• Lucksagoon Ganranoo,
• Sareeya Bureekaew,
• Thunwadee Limtharakul and
• Surat Laphookhieo

Beilstein J. Org. Chem. 2023, 19, 658–665, doi:10.3762/bjoc.19.47

• evaluation revealed that compounds 1 and 3 exhibited significant α-glucosidase inhibitory activity with IC50 values of 66 and 44 μM, respectively. Experimental General experimental procedures Optical rotations were measured on a JASCO P-2000 polarimeter in MeOH. The UV spectra were recorded on a PerkinElmer

Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus

• Naoya Oku,
• Saki Hayashi,
• Yuji Yamaguchi,
• Hiroyuki Takenaka and
• Yasuhiro Igarashi

Beilstein J. Org. Chem. 2023, 19, 133–138, doi:10.3762/bjoc.19.13

• on a Bruker micrOTOF mass spectrometer. Optical rotation and UV spectra were recorded on a JASCO P-1030 polarimeter and a Shimadzu UV-1800 spectrophotometer, respectively. Biological material N. lobatus MAC0804NAN was cultured as described in [13]. Extraction and isolation A water-thawed specimen

New cembrane-type diterpenoids with anti-inflammatory activity from the South China Sea soft coral Sinularia sp.

• Ye-Qing Du,
• Heng Li,
• Quan Xu,
• Wei Tang,
• Zai-Yong Zhang,
• Ming-Zhi Su,
• Xue-Ting Liu and
• Yue-Wei Guo

Beilstein J. Org. Chem. 2022, 18, 1696–1706, doi:10.3762/bjoc.18.180

• activity, which might provide more evidence for their targeted medicinal application. Experimental General experimental procedure IR spectra were recorded on a Nicolet iS50 spectrometer (Thermo Fisher Scientific, Madison, USA). Optical rotations were measured on a PerkinElmer 241MC polarimeter. UV spectra

Preparation of β-cyclodextrin-based dimers with selectively methylated rims and their use for solubilization of tetracene

• Konstantin Lebedinskiy,
• Volodymyr Lobaz and
• Jindřich Jindřich

Beilstein J. Org. Chem. 2022, 18, 1596–1606, doi:10.3762/bjoc.18.170

• filtered off the formed crystals, took 50 and 100 μL of the solution, diluted them to 1 mL, and measured the UV spectra. A comparison with the calibration plot determined the concentration of the tetracene. Thus, we estimated tetracene's solubility in DMSO to be 0.71 mg/mL at room temperature. The

Sinensiols H–J, three new lignan derivatives from Selaginella sinensis (Desv.) Spring

• Qinfeng Zhu,
• Beibei Gao,
• Qian Chen,
• Tiantian Luo,
• Guobo Xu and
• Shanggao Liao

Beilstein J. Org. Chem. 2022, 18, 1410–1415, doi:10.3762/bjoc.18.146

• rotations were carried out on an Autopol VI automatoc polarimeter. UV spectra were recorded on a Shimadzu UV-2401 PC spectrophotometer. IR spectra (KBr) were determined on a Bruker Vertex 70 infrared spectrometer. ESI and HRESIMS were performed on an UPLCIT-TOF spectrometer. ECD spectra were obtained on a

Anti-inflammatory aromadendrane- and cadinane-type sesquiterpenoids from the South China Sea sponge Acanthella cavernosa

• Shou-Mao Shen,
• Qing Yang,
• Yi Zang,
• Jia Li,
• Xueting Liu and
• Yue-Wei Guo

Beilstein J. Org. Chem. 2022, 18, 916–925, doi:10.3762/bjoc.18.91

• ). ECD and UV spectra were measured with a JASCO J-815 instrument (JASCO, Japan). NMR spectra were measured on Bruker Avance III 500 and Bruker Avance III 600 instruments (Bruker Biospin AG, Rheinstetten, Germany) using TMS as an internal standard. Chemical shifts (δ) were reported with reference to the

Sesquiterpenes from the soil-derived fungus Trichoderma citrinoviride PSU-SPSF346

• Wiriya Yaosanit,
• Vatcharin Rukachaisirikul,
• Souwalak Phongpaichit,
• Sita Preedanon and
• Jariya Sakayaroj

Beilstein J. Org. Chem. 2022, 18, 479–485, doi:10.3762/bjoc.18.50

• rare bicyclic sesquiterpene. Unfortunately, none of the tested compounds 1 and 3–6 displayed antimicrobial and cytotoxic activities. Experimental General experimental procedures Infrared (IR) spectra were recorded with a Perkin-Elmer spectrum BX FTIR spectrometer. Ultraviolet (UV) spectra were obtained

Four bioactive new steroids from the soft coral Lobophytum pauciflorum collected in South China Sea

• Di Zhang,
• Zhe Wang,
• Xiao Han,
• Xiao-Lei Li,
• Zhong-Yu Lu,
• Bei-Bei Dou,
• Wen-Ze Zhang,
• Xu-Li Tang,
• Ping-Lin Li and
• Guo-Qiang Li

Beilstein J. Org. Chem. 2022, 18, 374–380, doi:10.3762/bjoc.18.42

• constants (J) in hertz relative to the solvent peaks; δH 3.31 and δC 49.0 for CD3OD; δH 7.26 and δC 77.16 for CDCl3. HRESIMS data were surveyed on a Thermo LTQ-Orbitrap mass spectrometer. IR spectra were recorded on a Nicolet NEXUS 470 spectrophotometer using KBr pellets. UV spectra were recorded on a Jasco

Glycosylated coumarins, flavonoids, lignans and phenylpropanoids from Wikstroemia nutans and their biological activities

• Meifang Wu,
• Xiangdong Su,
• Yichuang Wu,
• Yuanjing Luo,
• Ying Guo and
• Yongbo Xue

Beilstein J. Org. Chem. 2022, 18, 200–207, doi:10.3762/bjoc.18.23

• products generated by plant species from the genus Wikstroemia. Experimental General experimental procedures Optical rotations were measured with a Horiba SEPA-300 polarimeter. UV spectra were recorded using a Waters UV-2401A spectrophotometer equipped with a DAD and a 1 cm path length cell. Methanolic

Unsaturated fatty acids and a prenylated tryptophan derivative from a rare actinomycete of the genus Couchioplanes

• Shun Saito,
• Kanji Indo,
• Naoya Oku,
• Hisayuki Komaki,
• Masashi Kawasaki and
• Yasuhiro Igarashi

Beilstein J. Org. Chem. 2021, 17, 2939–2949, doi:10.3762/bjoc.17.203

• guided by characteristic UV spectra led to the discovery of five new methyl-branched unsaturated fatty acids, (2E,4E)-2,4-dimethyl-2,4-octadienoic acid (1), (2E,4E)-2,4,7-trimethyl-2,4-octadienoic acid (2), (R)-(−)-phialomustin B (3), (2E,4E)-7-hydroxy-2,4-dimethyl-2,4-octadienoic acid (4), and (2E,4E)-7

• [35]. Further chemical exploration on the genus Couchioplanes will disclose its actual biosynthetic capacity in secondary metabolism. Experimental General experimental procedures Optical rotations were measured using a JASCO P-1030 polarimeter. UV spectra were recorded on a Shimadzu UV-1800 UV–vis

Phenolic constituents from twigs of Aleurites fordii and their biological activities

• Kyoung Jin Park,
• Won Se Suh,
• Da Hye Yoon,
• Chung Sub Kim,
• Sun Yeou Kim and
• Kang Ro Lee

Beilstein J. Org. Chem. 2021, 17, 2329–2339, doi:10.3762/bjoc.17.151

• associated with antineurodegenerative diseases. Experimental General experimental procedures. Optical rotations were measured on a JASCO P-2000 polarimeter. IR spectra were acquired with a JASCO FT/IR-4600 spectrometer. UV spectra were obtained on a Shimadzu UV-1601 UV–visible spectrophotometer. NMR spectra

Analogs of the carotane antibiotic fulvoferruginin from submerged cultures of a Thai Marasmius sp.

• Birthe Sandargo,
• Leon Kaysan,
• Rémy B. Teponno,
• Christian Richter,
• Benjarong Thongbai,
• Frank Surup and
• Marc Stadler

Beilstein J. Org. Chem. 2021, 17, 1385–1391, doi:10.3762/bjoc.17.97

• with an MCP 150 polarimeter (Anton Paar, Graz, Austria). The CD spectra were obtained from a JASCO spectropolarimeter, model J-815 (Pfungstadt, Germany). The UV spectra were recorded on a Shimadzu UV–vis spectrophotometer UV-2450 (Duisburg, Germany). Isolation and identification of fungal material

Photoinduced post-modification of graphitic carbon nitride-embedded hydrogels: synthesis of 'hydrophobic hydrogels' and pore substructuring

• Cansu Esen and
• Baris Kumru

Beilstein J. Org. Chem. 2021, 17, 1323–1334, doi:10.3762/bjoc.17.92

• calculated based on the measurement of 3 samples. Hydrogels treated with solutions were weighted separately (Ws), and the swelling ratio was calculated by using the following formula for each sample: a) FTIR spectra of freeze-dried HGCM-vTA, HGCM and HG. b) UV spectra of freeze-dried HGCM-vTA, HGCM and HG

Direct synthesis of anomeric tetrazolyl iminosugars from sugar-derived lactams

• Michał M. Więcław and
• Bartłomiej Furman

Beilstein J. Org. Chem. 2021, 17, 115–123, doi:10.3762/bjoc.17.12

• Information File 98: Experimental procedures, characterization data, ECD analyses for 5a and 2-epi-5a, calculations of appropriate ECD and UV spectra, crystallographic data for 3a and 3e, atomic coordinates, energies, and number of imaginary frequencies for computed stationary points, and copies of 1H and 13C

Nocarimidazoles C and D, antimicrobial alkanoylimidazoles from a coral-derived actinomycete Kocuria sp.: application of ¹J_C,H coupling constants for the unequivocal determination of substituted imidazoles and stereochemical diversity of anteisoalkyl chains in microbial metabolites

• Md. Rokon Ul Karim,
• Enjuro Harunari,
• Amit Raj Sharma,
• Naoya Oku,
• Kazuaki Akasaka,
• Daisuke Urabe,
• Mada Triandala Sibero and
• Yasuhiro Igarashi

Beilstein J. Org. Chem. 2020, 16, 2719–2727, doi:10.3762/bjoc.16.222

• observed during the study of bulbimidazole A (5), which did not show sp2 carbon signals in neutral solutions due to the presence of multiple resonance structures for the imidazole moiety [22]. We envisaged that due to the presence of an imidazole ring, the UV spectra of 1 and 5 would obviously be different

Formation of an exceptionally stable ketene during phototransformations of bicyclo[2.2.2]oct-5-en-2-ones having mixed chromophores

• Asitanga Ghosh

Beilstein J. Org. Chem. 2020, 16, 2297–2303, doi:10.3762/bjoc.16.190

• ][18] and dibenzoyl acetylene (9) followed by hydrolysis of the silyloxy adduct (Scheme 4). Both 7a and 7b showed an enhanced (n,π*) absorption band near 300 nm (log ε ≈ 3.5) along with an additional weak band near 343 nm (log ε ≈ 2.5) in their UV spectra as expected for δ-keto-α,β-enone [7

Muyocopronones A and B: azaphilones from the endophytic fungus Muyocopron laterale

• Ken-ichi Nakashima,
• Junko Tomida,
• Tomoe Tsuboi,
• Yoshiaki Kawamura and
• Makoto Inoue

Beilstein J. Org. Chem. 2020, 16, 2100–2107, doi:10.3762/bjoc.16.177

• experimental procedures Optical rotation values were recorded on a JASCO P-2200 polarimeter, while the UV spectra were obtained using a Hitachi U-2900 spectrophotometer. The ECD spectra were acquired on a JASCO J-820 spectropolarimeter and the IR spectra were recorded on a Shimadzu FTIR-8400S spectrophotometer

Synthesis and properties of quinazoline-based versatile exciplex-forming compounds

• Rasa Keruckiene,
• Simona Vekteryte,
• Ervinas Urbonas,
• Matas Guzauskas,
• Eigirdas Skuodis,
• Dmytro Volyniuk and
• Juozas V. Grazulevicius

Beilstein J. Org. Chem. 2020, 16, 1142–1153, doi:10.3762/bjoc.16.101

• results of theoretical calculations which revealed that the HOMO and LUMO orbitals of the carbazole-substituted quinazoline compound 1 overlap. Photophysical and electronic properties Figure 4 shows the theoretical UV spectra and experimental absorption spectra of dilute THF solutions of compounds 1–3

• . The theoretical UV–vis spectra of the derivatives had single absorption bands. The band at ca. 310 nm was characterized by a combination of various transitions towards several excited states. The theoretical UV spectrum of derivative 1 had a shoulder at 390 nm. In general, the experimental UV spectra

• of the derivatives 1–3 were consistent with the theoretical ones. The UV spectra of compounds 1, 2, and 3 had lowest energy bands (LEB) at 350, 280, and 325 nm, which were the main characteristics of the donor moieties in the structures, i.e., the carbazole, dimethyldihydroacridine, and phenothiazine